I know some UK blind people in the UK that have decent careers, I know others who have had a really hard time of it too.
Make sure you know your rights under the Equality Act 2010 and what support you can get from
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Large corporations, institutions and government should have the more enlightened policies on disabled employees.
I don't think you have to mention your disability on your job application but can wait until they invite you for interview and only tell them when they ask if you need any reasonable adjustments for the interview. At that point you can blast them with requests for documents in large print or to bring a "support worker" who will guide you to the interview room or may support you in any tests they give you.