Ariel and Verdana are often suggested, as those fonts don't have serifs. Point size is recommended to be between 12 and 18, dependent on the font (point size varies between fonts).

Atkinson hyperlegible and OpenDyslexic are two other custom options.

There have been a couple of fount families designed for better legibility by visually impaired people. One of them is called Tiresias.

> Tiresias is a family of TrueType sans-serif typefaces that were designed with the aim of legibility by people with impaired vision at the Scientific Research Unit of Royal National Institute of Blind People in London. The font was originally designed for the RNIB by Chris Sharville of Laker Sharville Design Associates who was working with John Gill at the time.

https://en.wikipedia.org/wiki/Tiresias_(typeface)

Tiresias Screenfont is widely used for closed captions (subtitles) on TVs.

There is some criticism of this

https://screenfont.ca/fonts/today/Tiresias/

I know you can get VoiceOver on macOS to tell you all about the font, whenever it changes. It's a best trick to use if a document doesn't have semantic headings and just changes the font. When you find a heading, you can even jump to the next use of that formatting.

There might be a similar feature on other screen readers. If you're feeling curious about this, it might be worth exploring different content and getting a sense for where people use different fonts, sizes and bold and italics.

I suppose you could think of fonts like accents and intonation. Some fonts look fancier, but are harder to read.

San serif fonts are usually said to be easier to read.

APHont