Ooh! I just bought a house 9mo ago and while it wasn't designed for accessibility, it has a few features that make it accessible and that I really like.
I was going to post a photo of my living room/kitchen, but I don't want someone to google image search it and find me since there's a very similar real estate listing out there... but basically it's lit like
$1 and it's amazing - 26 bright LED pot lights. This is the feature that sold me on the house (well, that and the floors). Most blind people have some remaining vision - it varies as to how usable it is.
What I don't like, though, are the front steps. They're uneven in height and need redone. That doesn't happen so much on interior steps, but still can on exterior ones. Mine also don't have a hand rail. If you have exterior steps, make them even and add a hand rail.
Make transitions between different rooms/flooring types as seamless as possible, no bumps, drops, strips that you can trip over, etc.
We have a giant butcher block island in the kitchen. My husband rounded the corners on it a bit which has saved my hip a couple of times.
Be consistent about where you place things like light switches and at least 1 electrical outlet in relation to doorways.
All of our bottom cabinets and the big, full-height ones beside our stove have drawers/shelves/racks that pull out, which makes it a lot easier to find what's in them.
Oh! One thing we've gotten into the habit of doing - we have a wire basket next to our kitchen sink and all of the sharp knives go into there, so that way no one cuts themselves when reaching into the sink while doing dishes and we know where the sharp ones will be. If you wanted to work something like this into the kitchen design, either as a part of the counter space or as a smaller, narrow little sink beside the main one, that might be cool.
Also the doorways in our house are slightly wider than average and I bump into them a lot less (I lack peripheral vision), so that's nice.
I don't know if this is something you'd be designing for or not, but the location of the hot water heater allows plenty of room to safely get around it and it has a no-brainer electric igniter on it that you don't really have to see to use. This has come in handy a time or two when I've had to re-light it because the city's been doing work and needed to turn the gas off.