Your best (and probably only) bet on Windows is Reaper. I've used it with NVDA to record and monitor my voice for some voice-acting work. You have to install Osara and SWS which enable accessibility and add script extensions. There's a website with some very helpful tutorials that should help you get off the ground. Reaper isn't free, but it costs $60US which is very cheap for a full-fledged DAW, and there's a 2-month trial period. Keep in mind, there are basically no instruments included with Reaper, so you'll have to bring your own sounds, and VSTs (basically virtual instruments) tend to not be particularly accessible. I use a mixer with a USB interface to plug in all my synths, but any recording device that's compatible with your computer will do in a pinch.
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If you can get access to something running iOS or Mac OS, you can try Garageband for free, and that has a ton of built-in instruments.