Hoo boy, get ready for a wild ride.
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First, start by acquiring some of your legal depressant of choice. I quite fancy rum and coke. Next, prepare your best arsenal of profanity and clear any young children from the area.
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Thirdly, follow this guide, preferably with NVDA,
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As a regular user of Steam and streamer, I will say, it's a royal pain, but it is doable. feel free to send me a PM (no live chats please. I can't read those) if you need help. That said, I did this with NVDA and not JAWS, so I can't speak to the JAWS procedure.