This has been known since the 1990's(?), or at least early 00's, I think. If anyone wants a book/paper(s) to read, I highly recommend Rythmns of the Brain by Gyorgy Buzaski. He's done fantastic work in the field, including finding the reason for theta oscillations and developing a more general (uncorroborated) theory for brain oscillation and their physical correlates. I also highly recommend N. Koppel and B. Ehrmentrout's and their students' work for people with a more mathematical leaning.

It always amazes me what you can do with optogenetics. It’s just so cool!

Is there any psychiatry defined condition which doesn't have some type of negative correlation under WCST (or nearly every other rule shift test)? It's bizarre that CogNeuro constructs generate so much similarity even when the underlying model physiology implies opposite function.

I'm a little confused by what this study adds to the body of evidence. Even if we assume that behavior is confined to hyperlocalized regions, how would those interactions update the global model without some type of interconnect? Unless each of these clusters had a complete state model (which would be absurdly inefficient), how else was this supposed to work?

In general, work which deals with memory and behavior and doesn't mention glia at all is probably worth assigning low weight. Eventually we need to start looking at the entire system instead of just the parts.

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