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Walking naturally after spinal cord injury using a brain–spine interface (nature.com)
submitted 1m ago by Robert_Larsson
Robert_Larsson [OP] 8 points 1m ago
**Abstract**
A spinal cord injury interrupts the communication between the brain and the region of the spinal cord that produces walking, leading to paralysis1,2. Here, we restored this communication with a digital bridge between the brain and spinal cord that enabled an individual with chronic tetraplegia to stand and walk naturally in community settings. This brain–spine interface (BSI) consists of fully implanted recording and stimulation systems that establish a direct link between cortical signals3 and the analogue modulation of epidural electrical stimulation targeting the spinal cord regions involved in the production of walking4,5,6. A highly reliable BSI is calibrated within a few minutes. This reliability has remained stable over one year, including during independent use at home. The participant reports that the BSI enables natural control over the movements of his legs to stand, walk, climb stairs and even traverse complex terrains. Moreover, neurorehabilitation supported by the BSI improved neurological recovery. The participant regained the ability to walk with crutches overground even when the BSI was switched off. This digital bridge establishes a framework to restore natural control of movement after paralysis.

CEO of Onward Medical Dave Marver explains how they made the breakthrough in Times Radio interview: https://youtu.be/xEBJh5HVGMA
SelfAwareMachine 4 points 1m ago
Ugghhhh wish they waited three months longer to publish, curious if it was obvious that this method was plateauing also. Also curious what this looks like without the prior implant and surgeries. Nearly all BCI devices I'm aware of lose efficacy over time, whether due to electrode degradation, gross signal/morphology changes, or homeostatic adaptation, will be super interested in the longitudinal follow ups.

I find the whole realm of stimulation of any sort (and drugs) imparting significant behavioral/functional/cognitive modification a really fascinating insight into the mechanics of our nervous system.

Edit: PR Links
Man with paralysis walks naturally after brain, spine implants - CNN

Paralysed man walks again via thought-controlled implants - MedXpress

Paralysed man walks using device that reconnects brain with muscles - Guardian
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