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New drug found to slow Alzheimer's hailed a 'turning point in fight against disease' (news.sky.com)

submitted 59m ago by ICumCoffee

ICumCoffee [OP] 1 points 41m ago

Drug is called Donanemab and it was found to slow "clinical decline" by up to 35%, allowing people with Alzheimer's to continue performing day-to-day tasks such as shopping, housekeeping, managing their finances and taking medication. Treatment with donanemab reduced amyloid plaque on average by 84% at 18 months, compared with a 1% decrease for participants given a placebo. A small number of people had some serious side effects such as brain swelling.

PhoenixTineldyer 1 points 23m ago

84% is *insane*.

ICumCoffee [OP] 1 points 11m ago

There's a reason why it is being called a "turning point". This is gonna be huge for Alzheimer's patients in coming years.

mjohnsimon 1 points 17m ago

I had to re-read that.

Holy shit

doctorkanefsky 1 points 4m ago

84% change in imaging findings, only 35% change in cognitive decline. The imaging finding is correlated but not necessarily causative, so we should be conservative about how we phrase the benefits of this medication.

tries4accuracy 1 points 10m ago

I think it’s also awesome that this was posted from the account of “I cum coffee”

Donut-Strong 1 points 49m ago

I will probably be on this in about 20 or so years

jaymobe07 1 points 19m ago

same. my grandmother had it. My dad is showing a lot of memory issues lately. Alzheimers is a cruel disease. To have your loved one still there, but yet not there.

Captain_CatDad 1 points 28m ago

I will definitely be, since it’s hereditary.

inmatenumberseven 1 points 5m ago

Start doing brain exercises! If you speak more than one language, make sure you’re using them both! Good luck.

Blind_Melone 1 points 31m ago

Watching my grandmother die of Alzheimers was one of the worst experiences I've had to go through.

PhoenixTineldyer 1 points 17m ago

My ex went through the same thing. He was deeply and profoundly changed by it.

sofaslippers 1 points 10m ago

I’m going through that right now. I’ll cherish my last visit with her. She was aware of who I was, and loved talking about my kids etc. My brother saw her last week and she had no idea who he was. She also didn’t know my dad (her son) either.

She just kept saying that she wants to see her mom, who died before I was born. It’s really heartbreaking, and part of me will feel some relief when she passes.

Blind_Melone 1 points 5m ago

I was gonna type a whole big thing out but when I started, I started to think a out the whole long drawn out process of her death, and it just felt like too much to spew out in a thread, so I kept it private.

I'm really sorry you're currently going through this, and yeah, I felt the same relief when she finally passed. Good on you for continuing to show her that support; it's hard to see someone you loved for so many years practically disappear in front of you.

pwendle 1 points 3m ago

My grandfather died with Alzheimer’s. He was a great man but I could never appreciate him bc he was losing it by the time I was 6 years old.

CurrentAir585 1 points 36m ago

The question is, can anyone outside the 1% afford it?

inmatenumberseven 1 points 4m ago

It’ll be covered by all the public health systems.

senortipton 1 points 17m ago

As far as I understand it this really needs to be administered before symptoms show.

icnoevil 1 points 48m ago

Too pricey for being only 25% effective

TranquilSeaOtter 1 points 29m ago

It's not like development will stop. Early cancer drugs weren't very effective either but decades later, survival rates are much higher.

OptimusSublime 1 points 43m ago

Conversely you can pay $0 for 0% effectiveness.

axlfrederick 1 points 35m ago

And death via Alzheimer’s is nasty

Graveborn-metal 1 points 30m ago

Did Samuel L Jackson get eaten by a shark so this drug could be made?

CellsInterlinked 1 points 27m ago

Quick, someone inject it into the president.

PhoenixTineldyer 1 points 16m ago

Person woman man camera TV

letdogsvote 1 points 17m ago

Trump's not in office anymore and besides he probably wouldn't take it unless it was slipped into a Diet Coke or maybe a hamberder with covfefe.

sofaslippers 1 points 8m ago

Is the fake news in the room with you right now?

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